Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834762 | 0.76 | MAPT (0.46) | MAPTKDM4ELMNAHTTMEN1 | |
| SCHEMBL8122719 | 0.71 | MAPT (0.47) | MAPTKDM4ELMNAHTTMEN1 | |
| Hydrochloric Acid SCHEMBL10396866 | 0.70 | MAPT (0.46) | MAPTKDM4ELMNAHTTMEN1 | |
| SCHEMBL8192297 | 0.70 | MAPT (0.46) | MAPTKDM4ELMNAHTTMEN1 | |
| SCHEMBL10339659 | 0.68 | MAPT (0.43) | MAPTKDM4ELMNAHTTMEN1 | |
| SCHEMBL17629238 | 0.68 | MAPT (0.47) | MAPTKDM4ELMNAHTTMEN1 | |
| SCHEMBL3293742 | 0.68 | MAPT (0.47) | MAPTKDM4ELMNAHTTMEN1 | |
| SCHEMBL217044 | 0.67 | MAPT (1.00) | MAPTKDM4ELMNAHTTMEN1 | |
| SCHEMBL6995462 | 0.67 | MAPT (0.46) | MAPTKDM4ELMNAHTTMEN1 | |
| SCHEMBL7730427 | 0.66 | MAPT (0.48) | MAPTKDM4ELMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554206-B | Synthetic taxol resistant cell strain H460TaxRMethods of inhibiting | 北京化工大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-116554206-A | Synthetic taxol resistant cell strain H460 TaxR Methods of inhibiting | 北京化工大学 | 2023-08-08 | — | — | CN | disclosed |