SCHEMBL2909935

SCHEMBL2909935

COc1cc2ncc(C(N)=O)c(Nc3ccc(Cl)c(Cl)c3)c2cc1N1CCCCC1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2911370 0.93 CSF1R (0.94) CSF1R
SCHEMBL2905491 0.92 CSF1R (1.00) CSF1R
SCHEMBL2912117 0.91 CSF1R (0.83) CSF1R
SCHEMBL2911366 0.90 CSF1R (0.83) CSF1R
SCHEMBL2904973 0.90 CSF1R (0.83) CSF1R
SCHEMBL2904695 0.89 CSF1R (1.00) CSF1R
SCHEMBL2910769 0.88 CSF1R (0.68) CSF1R
SCHEMBL2910805 0.84 CSF1R (0.79) CSF1R
SCHEMBL2904662 0.84 CSF1R (0.84) CSF1R
SCHEMBL2913383 0.84 CSF1R (0.71) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010496-B1 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS ASTRAZENECA AB (SE) 2010-08-25 EP disclosed