SCHEMBL29099377

SCHEMBL29099377

c1ccc2c(c1)c1ccccc1n2-c1ccc(-n2ccnc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.61
MEN1 O00255 1/20 0.59
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
KMT2A Q03164 1/20 0.59
LMNA P02545 1/20 0.53
MAPT P10636 1/20 0.53
ENPP2 Q13822 1/20 0.53
MKNK1 Q9BUB5 1/20 0.53
MKNK2 Q9HBH9 1/20 0.53
NOTUM Q6P988 1/20 0.53
KDM4E B2RXH2 1/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CYP11B1 P15538 2/20 0.51
CYP11B2 P19099 2/20 0.51
CYP19A1 P11511 1/20 0.51
CYP2A6 P11509 1/20 0.47
NPC1 O15118 1/20 0.47
CASP3 P42574 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29647885 1.00 CYP3A4 (0.61) CYP3A4MEN1ALOX15TSHRKMT2A
SCHEMBL15390058 0.88 CYP3A4 (0.56) CYP3A4MEN1ALOX15TSHRKMT2A
SCHEMBL15389367 0.88 CYP3A4 (0.56) CYP3A4MEN1ALOX15TSHRKMT2A
SCHEMBL28518290 0.85 CYP3A4 (0.56) CYP3A4MEN1ALOX15TSHRKMT2A
SCHEMBL24297756 0.82 CYP11B1 (0.49) CYP3A4MEN1ALOX15TSHRKMT2A
SCHEMBL280507 0.81 CYP11B1 (0.48) CYP3A4MEN1ALOX15TSHRKMT2A
SCHEMBL19072489 0.81 CYP3A4 (0.41) CYP3A4MEN1ALOX15TSHRKMT2A
SCHEMBL24297757 0.79 CYP11B1 (0.51) CYP3A4MEN1ALOX15TSHRKMT2A
SCHEMBL2532397 0.79 LMNA (0.78) CYP3A4MEN1ALOX15TSHRKMT2A
SCHEMBL451 0.77 CYP3A4 (1.00) CYP3A4MEN1ALOX15TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116568685-A Organic compound, carrier transporting material, host material, light-emitting device, electronic apparatus, and lighting device 株式会社半导体能源研究所 2023-08-08 CN disclosed