Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911298 | 0.84 | GSK3B (0.47) | GSK3BGSK3AGAACDK1 | |
| SCHEMBL2904612 | 0.81 | GSK3B (0.36) | GSK3BGSK3ACDK1 | |
| SCHEMBL2909549 | 0.80 | GSK3B (0.39) | GSK3BGSK3ACDK1 | |
| SCHEMBL2910738 | 0.80 | CYP1A2 (0.40) | — | |
| SCHEMBL2905411 | 0.78 | GSK3B (0.35) | GSK3BGSK3ACDK1 | |
| SCHEMBL2912527 | 0.78 | GSK3B (0.36) | GSK3BGSK3ACDK1 | |
| SCHEMBL2909967 | 0.78 | GSK3B (0.33) | GSK3BGSK3ACDK1 | |
| SCHEMBL2909974 | 0.78 | GSK3B (0.33) | GSK3BGSK3ACDK1 | |
| SCHEMBL2907486 | 0.78 | AXL (0.33) | GSK3BGSK3A | |
| SCHEMBL13455481 | 0.77 | GSK3B (0.37) | GSK3BGSK3ACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |