Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30825097 | 0.97 | NOTUM (0.50) | NOTUMAPPMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28452543 | 0.93 | MAPT (0.48) | NOTUMMAPTSMN1; SMN2ALDH1A1CYP2A6 | |
| SCHEMBL13021500 | 0.89 | ALDH1A1 (0.52) | APPMAPTSMN1; SMN2ALDH1A1CYP2A6 | |
| SCHEMBL5195266 | 0.89 | ALDH1A1 (0.52) | APPMAPTSMN1; SMN2ALDH1A1CYP2A6 | |
| SCHEMBL12294221 | 0.89 | ALDH1A1 (0.52) | APPMAPTSMN1; SMN2ALDH1A1CYP2A6 | |
| SCHEMBL7008365 | 0.89 | ALDH1A1 (0.52) | APPMAPTSMN1; SMN2ALDH1A1CYP2A6 | |
| SCHEMBL14408396 | 0.88 | ALDH1A1 (0.50) | APPMAPTALDH1A1CYP2A6ALDH3A1 | |
| SCHEMBL11937052 | 0.86 | ALDH1A1 (0.52) | APPMAPTALDH1A1CYP2A6ALDH3A1 | |
| SCHEMBL5873318 | 0.86 | ALDH1A1 (0.52) | APPMAPTALDH1A1CYP2A6ALDH3A1 | |
| SCHEMBL28436775 | 0.86 | ALDH1A1 (0.52) | APPMAPTALDH1A1CYP2A6ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768789-A | Aggregation-induced emission self-reporting photosensitizer probe and preparation method and application thereof | 南方医科大学南方医院 | 2023-09-19 | — | — | CN | disclosed |