Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29100007 | 0.91 | TGFBR1 (0.83) | TGFBR1TGFB1 | |
| SCHEMBL29100052 | 0.90 | TGFBR1 (0.84) | TGFBR1TGFB1 | |
| SCHEMBL29099978 | 0.90 | TGFBR1 (1.00) | TGFBR1TGFB1 | |
| SCHEMBL29099993 | 0.87 | TGFBR1 (0.79) | TGFBR1TGFB1 | |
| SCHEMBL29100045 | 0.86 | TGFBR1 (1.00) | TGFBR1TGFB1 | |
| SCHEMBL29099985 | 0.85 | TGFBR1 (0.82) | TGFBR1TGFB1 | |
| SCHEMBL29099927 | 0.83 | TGFBR1 (1.00) | TGFBR1TGFB1 | |
| SCHEMBL29099963 | 0.83 | TGFBR1 (0.75) | TGFBR1TGFB1 | |
| SCHEMBL29099959 | 0.81 | TGFBR1 (1.00) | TGFBR1TGFB1 | |
| SCHEMBL22186929 | 0.81 | TGFBR1 (0.75) | TGFBR1TGFB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196804-B | TGF-beta R1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-11-07 | — | — | CN | disclosed |