Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.58 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29100319 | 1.00 | TSHR (0.68) | TSHRALDH1A1CYP3A4ZDHHC20ZDHHC2 | |
| SCHEMBL16384955 | 0.87 | TSHR (0.70) | TSHRALDH1A1CYP3A4ZDHHC20ZDHHC2 | |
| SCHEMBL22840975 | 0.86 | TSHR (0.50) | TSHRALDH1A1CYP3A4ZDHHC20ZDHHC2 | |
| SCHEMBL16805863 | 0.85 | ZDHHC20 (0.56) | TSHRALDH1A1CYP3A4ZDHHC20ZDHHC2 | |
| SCHEMBL609025 | 0.85 | ZDHHC20 (0.67) | TSHRALDH1A1CYP3A4ZDHHC20ZDHHC2 | |
| SCHEMBL1043171 | 0.85 | TSHR (0.54) | TSHRALDH1A1CYP3A4ZDHHC20ZDHHC2 | |
| SCHEMBL15270326 | 0.84 | TSHR (0.66) | TSHRALDH1A1CYP3A4ZDHHC20ZDHHC2 | |
| SCHEMBL12570583 | 0.84 | TSHR (0.66) | TSHRALDH1A1CYP3A4ZDHHC20ZDHHC2 | |
| SCHEMBL26574747 | 0.84 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9485045 | 0.84 | ZDHHC20 (0.61) | TSHRALDH1A1CYP3A4ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924912-A | Molecule for improving hair toughness and application thereof | 江南大学 | 2023-10-24 | — | — | CN | claimed |
| CN-116924912-A | Molecule for improving hair toughness and application thereof | 江南大学 | 2023-10-24 | — | — | CN | disclosed |