SCHEMBL2910065

SCHEMBL2910065

CCCCOC(=O)NC(CSCc1ccc(OC)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 11/20 0.64
PPARG P37231 9/20 0.64
ACE P12821 8/20 0.61
PPARD Q03181 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2909471 0.92 PPARA (0.53) PPARAPPARGACEPPARD
SCHEMBL10937517 0.90 PPARA (0.61) PPARAPPARGACEPPARD
SCHEMBL2320402 0.84 FPR2 (0.54)
SCHEMBL8485515 0.84 FPR2 (0.54)
SCHEMBL9299417 0.84 PPARA (0.74) PPARAPPARGACEPPARD
SCHEMBL9299418 0.84 PPARA (0.74) PPARAPPARGACEPPARD
SCHEMBL1278177 0.82 PPARA (0.89) PPARAPPARGACEPPARD
SCHEMBL1278179 0.82 PPARA (0.89) PPARAPPARGACEPPARD
SCHEMBL11331399 0.82 PPARA (0.89) PPARAPPARGACEPPARD
SCHEMBL10659148 0.82 PPARA (0.64) PPARAPPARGACEPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2220081-A2 GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT LG Life Sciences Ltd. (KR) 2010-08-25 EP disclosed
WO-2009082152-A2 GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT LG LIFE SCIENCES LTD. (KR) 2009-07-02 WO disclosed
US-4058512-A Synthetic peptides having growth promoting activity AB KABI (SW) 1977-11-15 US disclosed