Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30676280 | 0.84 | POLB (0.46) | POLBHTTNPSR1MAPTKMT2A | |
| SCHEMBL15390791 | 0.84 | POLB (0.46) | POLBHTTNPSR1MAPTKMT2A | |
| SCHEMBL29837150 | 0.83 | POLB (0.39) | POLBHTTNPSR1TP53MAPT | |
| SCHEMBL19512762 | 0.83 | L3MBTL1 (0.42) | NPSR1KMT2AMEN1KDM4ETDP1 | |
| SCHEMBL29659142 | 0.83 | POLB (0.44) | POLBHTTNPSR1MAPTKMT2A | |
| SCHEMBL6601505 | 0.83 | POLB (0.44) | POLBHTTNPSR1MAPTKMT2A | |
| SCHEMBL8126885 | 0.81 | POLB (0.47) | POLBHTTNPSR1TP53MAPT | |
| SCHEMBL27845772 | 0.78 | POLB (0.38) | POLBHTTNPSR1TP53MAPT | |
| Alcohol SCHEMBL27538721 | 0.78 | POLB (0.44) | POLBHTTMAPTKMT2AMEN1 | |
| SCHEMBL7500028 | 0.77 | POLB (0.52) | POLBHTTTP53KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981667-A | Heterocyclic inhibitors of EGFR and/or HER2 for cancer treatment | 蝎子疗法股份有限公司 | 2023-10-31 | — | — | CN | disclosed |