SCHEMBL29100950

SCHEMBL29100950

CC(C)(O)c1cccc(CN=[N+]=[N-])c1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 1/20 0.31
PDE2A O00408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29994919 1.00 KAT2B (0.31) KAT2BPDE2A
SCHEMBL20436603 0.81 PDE2A (0.31) PDE2A
SCHEMBL20416694 0.76 NLRP3 (0.34)
SCHEMBL29100970 0.75 ACE2 (0.36)
SCHEMBL14270118 0.75 KAT2B (0.36) KAT2B
SCHEMBL20096042 0.72 KAT2B (0.35) KAT2B
SCHEMBL16401940 0.72 HTR2A (0.39)
SCHEMBL28770884 0.70 IDO1 (0.46) KAT2BPDE2A
SCHEMBL28698315 0.70 CYP4F2 (0.40) PDE2A
SCHEMBL29467954 0.70 CYP4F2 (0.40) PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116981669-A Pyrimidine or pyrido heterocyclic adenosine receptor inhibitor, preparation method and application thereof 上海齐鲁制药研究中心有限公司 2023-10-31 CN disclosed