Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16415508 | 0.84 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1873215 | 0.83 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10211016 | 0.83 | GAA (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL12787269 | 0.82 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11734492 | 0.81 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL15344 | 0.79 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL9005312 | 0.78 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL155563 | 0.78 | GAA (0.78) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL31260805 | 0.78 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL5074741 | 0.78 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2011-03-17 | — | — | US | disclosed |
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2011-03-17 | — | — | US | disclosed |
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2011-03-17 | — | — | US | disclosed |
| EP-2223909-A1 | Process for preparing pentanoic diacid derivatives | Ratiopharm GmbH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-2223909-A1 | Process for preparing pentanoic diacid derivatives | Ratiopharm GmbH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-2181089-A2 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | Ratiopharm GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009027081-A2 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009027081-A2 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2009-03-05 | — | — | WO | disclosed |
| WO-2007107276-A2 | PROCESS FOR PREPARING C7 INTERMEDIATES AND THEIR USE IN THE PREPARATION OF N-SUBSTITUTED PYRROLE DERIVATIVES | RATIOPHARM GMBH (DE) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007107276-A2 | PROCESS FOR PREPARING C7 INTERMEDIATES AND THEIR USE IN THE PREPARATION OF N-SUBSTITUTED PYRROLE DERIVATIVES | RATIOPHARM GMBH (DE) | 2007-09-27 | — | — | WO | disclosed |
| EP-1834944-A1 | Process for preparing C7 intermediates and their use in the preparation on N-substituted pyrrole derivatives | Ratiopharm GmbH (DE) | 2007-09-19 | — | — | EP | disclosed |
| EP-1834944-A1 | Process for preparing C7 intermediates and their use in the preparation on N-substituted pyrrole derivatives | Ratiopharm GmbH (DE) | 2007-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | HMGCR, DPYD, FDPS | GAA 744/4885MGAM 1973/4885SI 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.