SCHEMBL29101191

SCHEMBL29101191

Cc1ccnc(N)c1C.[Cd]

nearest known ligand 0.95

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 9/20 0.95
NOS3 P29474 8/20 0.95
NOS1 P29475 5/20 0.50
CCR1 P32246 1/20 0.41
CCR5 P51681 1/20 0.41
CCR8 P51685 1/20 0.41
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
LIMK1 P53667 2/20 0.37
F12 P00748 1/20 0.37
PLAU P00749 1/20 0.37
NCF1 P14598 1/20 0.37
BACE1 P56817 1/20 0.37
AKT1 P31749 2/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
PSMD14 O00487 1/20 0.32
COPS5 Q92905 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29814771 0.97
SCHEMBL34938 0.97
Zinc Ion SCHEMBL30519352 0.95 NOS2 (0.95) NOS2NOS3NOS1CCR1CCR5
SCHEMBL30454704 0.95 NOS2 (0.95) NOS2NOS3NOS1CCR1CCR5
Bromide SCHEMBL28053084 0.95 NOS2 (0.95) NOS2NOS3NOS1CCR1CCR5
SCHEMBL30482664 0.95 NOS2 (0.95) NOS2NOS3NOS1CCR1CCR5
SCHEMBL28572816 0.95 NOS2 (0.95) NOS2NOS3NOS1CCR1CCR5
Hydrochloric Acid SCHEMBL11719745 0.95 NOS2 (0.95) NOS2NOS3NOS1CCR1CCR5
SCHEMBL28237608 0.95 NOS2 (0.95) NOS2NOS3NOS1CCR1CCR5
Ammonia Solution, Strong SCHEMBL27445766 0.95 NOS2 (0.95) NOS2NOS3NOS1CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115337398-B ATP-responsive nano-drug for combined treatment of tumor chemotherapy and photodynamic therapy and preparation method thereof 大连理工大学 2023-09-12 CN disclosed