Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14110260 | 0.77 | EPHX2 (0.42) | NFKB1NFKB2RELAGAACA1 | |
| SCHEMBL28317671 | 0.72 | TP53 (0.33) | CA1CA12CA9CA2 | |
| SCHEMBL24438499 | 0.72 | GAA (0.46) | NFKB1NFKB2RELAGAACA1 | |
| SCHEMBL1559072 | 0.72 | CA1 (0.38) | NFKB1NFKB2RELAGAACA1 | |
| SCHEMBL16166476 | 0.69 | GAA (0.39) | NFKB1NFKB2RELAGAACA1 | |
| SCHEMBL30889135 | 0.68 | GAA (0.48) | NFKB1NFKB2RELAGAACA1 | |
| SCHEMBL4151983 | 0.68 | ATR (0.39) | NFKB1NFKB2RELAGAACA1 | |
| SCHEMBL22447140 | 0.67 | KDM4E (0.47) | NFKB1NFKB2RELAALDH1A1KMT2A | |
| SCHEMBL28607649 | 0.66 | CA1 (0.33) | NFKB1NFKB2RELAGAACA1 | |
| SCHEMBL31252831 | 0.66 | DRD2 (0.35) | NFKB1NFKB2RELACYP17A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997547-A | Granulin precursor modulators and methods of use thereof | 阿库达医疗公司 | 2023-11-03 | — | — | CN | disclosed |