Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050196 | 1.00 | TSHR (0.37) | TSHRLMNADNM1THRBOPRM1 | |
| SCHEMBL6050201 | 0.96 | TSHR (0.37) | TSHRLMNADNM1OPRM1 | |
| SCHEMBL6050246 | 0.91 | TSHR (0.32) | TSHR | |
| SCHEMBL6050145 | 0.91 | TSHR (0.37) | TSHRLMNADNM1THRBOPRM1 | |
| SCHEMBL3474884 | 0.89 | TSHR (0.39) | TSHRLMNADNM1THRBOPRM1 | |
| SCHEMBL24044418 | 0.89 | TSHR (0.46) | TSHRLMNADNM1THRBOPRM1 | |
| SCHEMBL985792 | 0.89 | TSHR (0.46) | TSHRLMNADNM1THRBOPRM1 | |
| SCHEMBL4745188 | 0.89 | TSHR (0.46) | TSHRLMNADNM1THRBOPRM1 | |
| SCHEMBL15211724 | 0.89 | TSHR (0.46) | TSHRLMNADNM1THRBOPRM1 | |
| SCHEMBL12844942 | 0.89 | TSHR (0.46) | TSHRLMNADNM1THRBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600803-A | Macrocyclic urea orexin receptor agonists | 默沙东有限责任公司 | 2023-08-15 | — | — | CN | claimed |
| CN-116600803-A | Macrocyclic urea orexin receptor agonists | 默沙东有限责任公司 | 2023-08-15 | — | — | CN | disclosed |