Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 4/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050145 | 0.98 | TSHR (0.37) | TSHROPRM1LMNADNM1FDPS | |
| SCHEMBL3428498 | 0.93 | TSHR (0.40) | TSHRDNM1 | |
| SCHEMBL6050196 | 0.89 | TSHR (0.37) | TSHROPRM1LMNADNM1FDPS | |
| SCHEMBL29102703 | 0.89 | TSHR (0.37) | TSHROPRM1LMNADNM1FDPS | |
| SCHEMBL1131040 | 0.88 | TSHR (0.48) | TSHROPRM1LMNADNM1FDPS | |
| SCHEMBL3429100 | 0.86 | — | — | |
| SCHEMBL24044418 | 0.85 | TSHR (0.46) | TSHROPRM1LMNADNM1FDPS | |
| SCHEMBL12844942 | 0.85 | TSHR (0.46) | TSHROPRM1LMNADNM1FDPS | |
| SCHEMBL4745188 | 0.85 | TSHR (0.46) | TSHROPRM1LMNADNM1FDPS | |
| SCHEMBL366647 | 0.85 | TSHR (0.46) | TSHROPRM1LMNADNM1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142836-A1 | SYNTHESIS OF TTX INTERMEDIATES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2010-12-16 | — | — | WO | disclosed |