Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 20/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826354 | 1.00 | GLP1R (0.50) | GLP1RHTR1ACYP2C8KCNH2 | |
| SCHEMBL29103523 | 1.00 | GLP1R (0.50) | GLP1RHTR1ACYP2C8KCNH2 | |
| SCHEMBL25089759 | 0.92 | GLP1R (0.51) | GLP1RHTR1ACYP2C8KCNH2 | |
| SCHEMBL24791812 | 0.92 | GLP1R (0.51) | GLP1RHTR1ACYP2C8KCNH2 | |
| SCHEMBL27477879 | 0.91 | GLP1R (0.50) | GLP1RHTR1ACYP2C8KCNH2 | |
| SCHEMBL25089540 | 0.89 | GLP1R (0.58) | GLP1RHTR1ACYP2C8KCNH2 | |
| SCHEMBL29103599 | 0.89 | GLP1R (0.58) | GLP1RHTR1ACYP2C8KCNH2 | |
| SCHEMBL29826147 | 0.89 | GLP1R (0.58) | GLP1RHTR1ACYP2C8KCNH2 | |
| SCHEMBL22402435 | 0.87 | GLP1R (0.43) | GLP1R | |
| SCHEMBL30899101 | 0.87 | GLP1R (0.43) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |