Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104551 | 0.81 | HRH3 (0.41) | PDE10AHRH3 | |
| SCHEMBL28913940 | 0.80 | HRH3 (0.56) | HRH3 | |
| SCHEMBL21624871 | 0.78 | HRH3 (0.47) | PDE10AHRH3 | |
| SCHEMBL21624875 | 0.78 | HRH3 (0.47) | PDE10AHRH3 | |
| SCHEMBL28542435 | 0.78 | HRH3 (0.55) | HRH3 | |
| SCHEMBL16620603 | 0.77 | TRPV1 (0.43) | HRH3 | |
| SCHEMBL28624613 | 0.77 | KDM4E (0.50) | HRH3 | |
| SCHEMBL22655595 | 0.76 | GRM1 (0.45) | HRH3 | |
| SCHEMBL22491830 | 0.76 | GRM1 (0.45) | HRH3 | |
| SCHEMBL28607394 | 0.74 | HRH3 (0.48) | PDE10AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015536-A | 2- (indazol-5-yl) -6- (piperidin-4-yl) -1, 7-naphthyridine derivatives and related compounds as modulators of nucleic acid splicing and treatment of proliferative diseases | 雷密克斯医疗公司 | 2023-11-07 | — | — | CN | disclosed |