Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 12/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543561 | 0.92 | HRH3 (0.61) | HRH3HRH4CCNCCDK8BTK | |
| SCHEMBL16620603 | 0.86 | TRPV1 (0.43) | HRH3ACACB | |
| SCHEMBL17626627 | 0.81 | HRH3 (0.60) | HRH3HRH4ACACB | |
| SCHEMBL17626880 | 0.81 | HRH3 (0.60) | HRH3HRH4ACACB | |
| SCHEMBL18691293 | 0.81 | HRH3 (0.60) | HRH3HRH4ACACB | |
| SCHEMBL28639336 | 0.79 | EIF2AK4 (0.43) | BTKACACB | |
| SCHEMBL28913940 | 0.79 | HRH3 (0.56) | HRH3 | |
| SCHEMBL16685016 | 0.79 | LSS (0.47) | HRH3 | |
| SCHEMBL29104563 | 0.78 | PDE10A (0.46) | HRH3 | |
| SCHEMBL4336110 | 0.78 | TRPV1 (0.48) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135175-B | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2021-04-06 | — | — | CN | disclosed |