Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569377 | 1.00 | CASP3 (0.48) | CASP3SENP8SENP7SENP6EDNRA | |
| SCHEMBL30569440 | 0.81 | CASP3 (0.38) | CASP3SENP8SENP7SENP6EDNRA | |
| SCHEMBL30569463 | 0.79 | CASP3 (0.44) | CASP3SENP8SENP7SENP6EDNRA | |
| SCHEMBL29104663 | 0.79 | CASP3 (0.44) | CASP3SENP8SENP7SENP6EDNRA | |
| SCHEMBL29104665 | 0.78 | CASP3 (0.46) | CASP3SENP8SENP7SENP6EDNRA | |
| SCHEMBL29104623 | 0.78 | CASP3 (0.46) | CASP3SENP8SENP7SENP6EDNRA | |
| SCHEMBL30569445 | 0.78 | CASP3 (0.46) | CASP3SENP8SENP7SENP6EDNRA | |
| SCHEMBL30569472 | 0.78 | CASP3 (0.46) | CASP3SENP8SENP7SENP6EDNRA | |
| SCHEMBL24470977 | 0.77 | EDNRA (0.56) | CASP3SENP8SENP7SENP6EDNRA | |
| SCHEMBL30569414 | 0.77 | EDNRA (0.56) | CASP3SENP8SENP7SENP6EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |