Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909574 | 1.00 | SYK (0.45) | SYKUSP2AKT1L3MBTL1CTSS | |
| SCHEMBL1341914 | 0.80 | PPARA (0.57) | USP2L3MBTL1CTSSPPARA | |
| SCHEMBL1343633 | 0.80 | PPARA (0.57) | USP2L3MBTL1CTSSPPARA | |
| SCHEMBL2598790 | 0.78 | SYK (0.59) | SYKAKT1L3MBTL1CTSSCTSL | |
| SCHEMBL12183918 | 0.77 | SYK (0.52) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL2597798 | 0.76 | SYK (0.63) | SYKL3MBTL1CTSSPPARAATM | |
| SCHEMBL12471858 | 0.76 | SYK (0.57) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL29662650 | 0.73 | CTSS (0.42) | SYKAKT1L3MBTL1CTSSCTSL | |
| SCHEMBL5724472 | 0.73 | SYK (0.59) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL4273683 | 0.72 | SYK (0.58) | SYKAKT1CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220055-A2 | NOVEL HETEROCYCLYL COMPOUNDS AND THEIR USE AS CHEMOKINE ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009010429-A2 | NOVEL HETEROCYCLYL COMPOUNDS AND THEIR USE AS CHEMOKINE ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-01-22 | — | — | WO | disclosed |