Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910604 | 1.00 | LMNA (0.46) | LMNAALDH1A1CYP1A2KMT2APTGS2 | |
| SCHEMBL2165990 | 0.90 | LMNA (0.53) | LMNAALDH1A1CYP1A2KMT2APTGS2 | |
| SCHEMBL2117754 | 0.90 | LMNA (0.53) | LMNAALDH1A1CYP1A2KMT2APTGS2 | |
| SCHEMBL2117755 | 0.90 | LMNA (0.53) | LMNAALDH1A1CYP1A2KMT2APTGS2 | |
| Hydrochloric Acid SCHEMBL28409325 | 0.88 | LMNA (0.51) | LMNAALDH1A1CYP1A2KMT2APTGS2 | |
| SCHEMBL5663819 | 0.84 | KMT2A (0.58) | ALDH1A1KMT2AGAAKDM4EMEN1 | |
| SCHEMBL5663817 | 0.84 | KMT2A (0.58) | ALDH1A1KMT2AGAAKDM4EMEN1 | |
| SCHEMBL61631 | 0.84 | CYP1A2 (0.54) | ALDH1A1CYP1A2PTGS1HDAC3ADAM17 | |
| Hydrochloric Acid SCHEMBL27615734 | 0.82 | CYP1A2 (0.52) | CYP1A2PTGS1HDAC3ADAM17HDAC1 | |
| SCHEMBL1776119 | 0.79 | KMT2A (0.48) | ALDH1A1CYP1A2KMT2APTGS1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220027-A1 | NEW POLYMORPHIC FORMS OF N-Ý4-(TRIFLUOROMETHYL)BENZYL¨-4-METHOXYBUTYRAMIDE | LABORATORIO FARMACEUTICO C.T. S.r.l. (IT) | 2010-08-25 | — | — | EP | claimed |
| WO-2009062949-A1 | NEW POLYMORPHIC FORMS OF N-[4-(TRIFLUOROMETHYL)BENZYL]-4-METHOXYBUTYRAMIDE | LABORATORIO FARMACEUTICO C.T. S.R.L. (IT) | 2009-05-22 | — | — | WO | claimed |
| EP-2220027-A1 | NEW POLYMORPHIC FORMS OF N-Ý4-(TRIFLUOROMETHYL)BENZYL¨-4-METHOXYBUTYRAMIDE | LABORATORIO FARMACEUTICO C.T. S.r.l. (IT) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009062949-A1 | NEW POLYMORPHIC FORMS OF N-[4-(TRIFLUOROMETHYL)BENZYL]-4-METHOXYBUTYRAMIDE | LABORATORIO FARMACEUTICO C.T. S.R.L. (IT) | 2009-05-22 | — | — | WO | disclosed |