SCHEMBL2910751 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CSF1R	P07333	11/20	0.68

▸	KCNH2	Q12809	5/20	0.64

▸	SCN5A	Q14524	4/20	0.64

▸	GAA	P10253	2/20	0.54

▸	MAPT	P10636	2/20	0.54

▸	THRB	P10828	1/20	0.54

▸	MEN1	O00255	1/20	0.53

▸	SLC2A1	P11166	1/20	0.53

▸	KMT2A	Q03164	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2912939	0.95	CSF1R (0.71)	CSF1RKCNH2SCN5AGAAMAPT
SCHEMBL2904648	0.92	CSF1R (0.79)	CSF1RKCNH2SCN5AGAAMEN1
SCHEMBL2909680	0.92	CSF1R (0.79)	CSF1RKCNH2SCN5AGAAMAPT
SCHEMBL2911044	0.91	CSF1R (0.69)	CSF1RKCNH2SCN5AGAAMEN1
SCHEMBL2911256	0.89	KCNH2 (0.76)	CSF1RKCNH2SCN5AGAAMEN1
SCHEMBL2909850	0.89	CSF1R (0.66)	CSF1RKCNH2SCN5AGAAMAPT
SCHEMBL2912249	0.89	KCNH2 (0.64)	CSF1RKCNH2SCN5AGAAMAPT
SCHEMBL2909797	0.89	CSF1R (0.85)	CSF1RKCNH2SCN5A
SCHEMBL2914041	0.88	CSF1R (0.69)	CSF1RKCNH2SCN5AGAAMAPT
SCHEMBL2905267	0.88	KCNH2 (0.65)	CSF1RKCNH2SCN5AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2010496-B1	4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS	ASTRAZENECA AB (SE)	2010-08-25	—	—	EP	disclosed