Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 11/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.71 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910751 | 0.95 | CSF1R (0.68) | CSF1RKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL2911029 | 0.92 | CSF1R (0.84) | CSF1RKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL2907668 | 0.92 | KCNH2 (0.70) | CSF1RKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL2911902 | 0.91 | CSF1R (0.85) | CSF1RKCNH2SCN5A | |
| SCHEMBL2905716 | 0.91 | CSF1R (0.73) | CSF1RKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL2905342 | 0.89 | KCNH2 (0.84) | CSF1RKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL2912843 | 0.89 | KCNH2 (0.73) | CSF1RKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL2909672 | 0.89 | KCNH2 (0.71) | CSF1RKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL2910402 | 0.89 | KCNH2 (0.64) | CSF1RKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL2909944 | 0.89 | CSF1R (0.78) | CSF1RKCNH2SCN5AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |