Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 10/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PPP1CA | P62136 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | MARS1 | P56192 | 2/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910701 | 0.88 | SMN1; SMN2 (0.47) | RPA1SMN1; SMN2MEN1KMT2AKDM5A | |
| SCHEMBL27638722 | 0.85 | RPA1 (0.61) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 | |
| SCHEMBL2912938 | 0.85 | RPA1 (0.48) | RPA1SMN1; SMN2PPP1CAL3MBTL1KDM5A | |
| SCHEMBL5270007 | 0.81 | PPP1CA (0.47) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 | |
| SCHEMBL5269052 | 0.79 | RPA1 (0.44) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 | |
| SCHEMBL27668671 | 0.74 | SMN1; SMN2 (0.43) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 | |
| SCHEMBL27648500 | 0.74 | PPP1CA (0.45) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 | |
| SCHEMBL5976456 | 0.73 | MARS1 (0.49) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 | |
| SCHEMBL27619816 | 0.73 | RPA1 (0.45) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 | |
| SCHEMBL2919032 | 0.73 | CA9 (0.57) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |