Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26207994 | 1.00 | CHRM3 (0.43) | CHRM3L3MBTL1POLBBRD4HDAC8 | |
| SCHEMBL26997852 | 0.90 | BRD4 (0.36) | CHRM3L3MBTL1POLBBRD4MEN1 | |
| SCHEMBL27428417 | 0.85 | CHRM3 (0.39) | CHRM3L3MBTL1POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL26724232 | 0.83 | CHRM3 (0.38) | CHRM3L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL26209176 | 0.82 | CHRM3 (0.38) | CHRM3L3MBTL1HTTSMN1; SMN2GLP1R | |
| SCHEMBL26999907 | 0.81 | CHRM3 (0.45) | CHRM3L3MBTL1POLBHDAC8HDAC6 | |
| SCHEMBL24579154 | 0.81 | CHRM3 (0.42) | CHRM3L3MBTL1POLBFFAR1 | |
| SCHEMBL10021553 | 0.81 | CHRM3 (0.42) | CHRM3L3MBTL1POLBFFAR1 | |
| SCHEMBL24577997 | 0.81 | CHRM3 (0.40) | CHRM3L3MBTL1POLBHTTGLP1R | |
| SCHEMBL26728235 | 0.81 | CHRM3 (0.42) | CHRM3L3MBTL1POLBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802184-A | Pyrazolothiazole carboxamides and their use as PDGFR inhibitors | 埃科特莱茵药品有限公司 | 2023-09-22 | — | — | CN | disclosed |