Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FHIT | P49789 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26208235 | 0.87 | CHRM3 (0.39) | CHRM3L3MBTL1FHITPOLBMEN1 | |
| SCHEMBL26208211 | 0.86 | CHRM3 (0.43) | CHRM3L3MBTL1FHITPOLBHCRTR2 | |
| SCHEMBL26208635 | 0.85 | CHRM3 (0.46) | CHRM3L3MBTL1POLBGLP1R | |
| SCHEMBL26724258 | 0.85 | CHRM3 (0.44) | CHRM3L3MBTL1POLBHTT | |
| SCHEMBL26997773 | 0.82 | CHRM3 (0.42) | CHRM3L3MBTL1POLBHTTALDH1A1 | |
| SCHEMBL26207994 | 0.81 | CHRM3 (0.43) | CHRM3L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL29108917 | 0.81 | CHRM3 (0.43) | CHRM3L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL26999935 | 0.78 | CHRM3 (0.44) | CHRM3L3MBTL1POLBGLP1R | |
| SCHEMBL3828293 | 0.78 | POLB (0.38) | L3MBTL1FHITPOLBHCRTR2HDAC8 | |
| SCHEMBL26724256 | 0.77 | CHRM3 (0.42) | CHRM3L3MBTL1POLBHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | CHRM3 179/4885L3MBTL1 4285/4885FHIT 4710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.