SCHEMBL29109356

SCHEMBL29109356

C[C@H](N)C1=Cc2ccsc2S(=O)(=O)N1c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29109295 0.82
SCHEMBL29109328 0.78 PIK3CD (0.31) MEN1POLBKMT2A
SCHEMBL29109351 0.73
SCHEMBL29109348 0.72 PIK3CD (0.40)
SCHEMBL29109339 0.72 PIK3R1 (0.39)
SCHEMBL29109283 0.72 PIK3CD (0.31)
SCHEMBL29109352 0.72 PIK3CD (0.40)
SCHEMBL29109282 0.72 PIK3CD (0.31)
SCHEMBL30604511 0.72 PIK3CD (0.31)
SCHEMBL29109342 0.72 PIK3R1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117088867-A Inhalable aromatic ring thiazide and analogue, pharmaceutical composition containing inhalable aromatic ring thiazide and analogue and application of inhalable aromatic ring thiazide and analogue in anti-inflammatory and anti-tumor 杭州百诚医药科技股份有限公司 2023-11-21 CN disclosed