Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 14/20 | 1.00 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | MELK | Q14680 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910261 | 0.87 | CSF1R (0.76) | CSF1RSLC2A1MEN1GAAKMT2A | |
| SCHEMBL2913485 | 0.84 | CSF1R (1.00) | CSF1RKCNH2SCN5A | |
| SCHEMBL2912321 | 0.84 | CSF1R (1.00) | CSF1RSLC2A1KCNH2SCN5A | |
| SCHEMBL2904695 | 0.83 | CSF1R (1.00) | CSF1RKCNH2SCN5A | |
| SCHEMBL2905491 | 0.83 | CSF1R (1.00) | CSF1RKCNH2SCN5A | |
| SCHEMBL2904662 | 0.82 | CSF1R (0.84) | CSF1RKCNH2SCN5A | |
| SCHEMBL2904669 | 0.81 | CSF1R (0.83) | CSF1RKCNH2SCN5A | |
| SCHEMBL2911370 | 0.80 | CSF1R (0.94) | CSF1RKCNH2SCN5A | |
| SCHEMBL2910805 | 0.79 | CSF1R (0.79) | CSF1RKCNH2SCN5A | |
| SCHEMBL2905216 | 0.79 | CSF1R (1.00) | CSF1RKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |