Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388946 | 0.85 | ABL1 (0.49) | ABL1ALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL8784058 | 0.80 | ABL1 (0.44) | ABL1ALDH1A1RAB9AKMT2APOLB | |
| SCHEMBL8784262 | 0.80 | ABL1 (0.50) | ABL1ALDH1A1MAPK1RAB9AKMT2A | |
| SCHEMBL8783964 | 0.77 | POLB (0.45) | ABL1ALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL29110340 | 0.77 | POLB (0.48) | ABL1ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL3515912 | 0.74 | CFTR (0.53) | CYP11B2ABL1ALDH1A1MAPK1NR4A2 | |
| SCHEMBL8784727 | 0.73 | POLB (0.40) | ABL1ALDH1A1RAB9AKDM4EPOLB | |
| SCHEMBL8784194 | 0.73 | CYP4F2 (0.40) | ABL1ALDH1A1KDM4EPOLBALOX15 | |
| SCHEMBL27388939 | 0.72 | ABL1 (0.51) | ABL1KMT2AKDM4EPOLBALOX15 | |
| SCHEMBL8784285 | 0.72 | POLB (0.42) | ABL1ALDH1A1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903613-A | 2-oxo quinazoline five-membered heterocyclic derivative, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-10-20 | — | — | CN | disclosed |