Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 18/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 17/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008327 | 0.85 | CCNT1 (0.45) | CDK9CCNT1BTK | |
| SCHEMBL30603869 | 0.84 | CCNT1 (0.55) | CDK9CCNT1 | |
| SCHEMBL22476358 | 0.84 | CCNT1 (0.55) | CDK9CCNT1 | |
| SCHEMBL22476348 | 0.81 | CCNT1 (0.41) | CDK9CCNT1BTK | |
| SCHEMBL5663907 | 0.77 | CCNT1 (0.53) | CDK9CCNT1 | |
| SCHEMBL27393222 | 0.77 | BTK (0.47) | DHFRCDK9CCNT1BTK | |
| SCHEMBL30973133 | 0.75 | JAK1 (0.44) | CDK9CCNT1 | |
| SCHEMBL27392698 | 0.75 | JAK1 (0.44) | CDK9CCNT1 | |
| SCHEMBL31711740 | 0.73 | DHFR (0.49) | DHFRCDK9CCNT1BTK | |
| SCHEMBL27392613 | 0.73 | DHFR (0.49) | DHFRCDK9CCNT1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854709-A | Reversible inhibitors of Bruton's tyrosine kinase and application thereof | 药雅科技(上海)有限公司 | 2023-10-10 | — | — | CN | disclosed |