Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2908231 | 0.99 | CHRNA7 (0.57) | CHRNA7HTR3ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2911620 | 0.89 | CHRNA7 (0.61) | CHRNA7HTR3ANPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2912834 | 0.88 | CHRNA7 (0.60) | CHRNA7HTR3ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2912984 | 0.86 | CHRNA7 (0.70) | CHRNA7HTR3A | |
| Hydrochloric Acid SCHEMBL2908418 | 0.85 | CHRNA7 (0.69) | CHRNA7HTR3A | |
| SCHEMBL7556010 | 0.83 | CHRNA7 (0.71) | CHRNA7HTR3A | |
| SCHEMBL3248601 | 0.82 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2QSOX1ALDH1A1 | |
| SCHEMBL2911803 | 0.82 | CHRNA7 (0.61) | CHRNA7HTR3ANPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3248272 | 0.82 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2QSOX1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2911682 | 0.81 | CHRNA7 (0.60) | CHRNA7HTR3ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987033-B1 | DIAZABICYCLOALKANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2010-08-25 | — | — | EP | claimed |
| US-20090075983-A1 | Novel Diazabicycloalkane Derivatives and Their Medical Use | NEUROSEARCH A/S (DK) | 2009-03-19 | — | — | US | claimed |
| EP-1987033-B1 | DIAZABICYCLOALKANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2010-08-25 | — | — | EP | disclosed |
| US-20090075983-A1 | Novel Diazabicycloalkane Derivatives and Their Medical Use | NEUROSEARCH A/S (DK) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075983-A1 | Novel Diazabicycloalkane Derivatives and Their Medical Use | CHRNA6, CHRNA2, CHRNA7 | CHRNA7 3/4885HTR3A 165/4885NPC1 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.