Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15542419 | 0.76 | ESR1 (0.50) | ESR1ESR2SMN1; SMN2KDM4E | |
| SCHEMBL30042841 | 0.76 | ESR1 (0.39) | ESR1ESR2KMT2ASMN1; SMN2 | |
| SCHEMBL13297359 | 0.76 | ESR1 (0.39) | ESR1ESR2KMT2A | |
| SCHEMBL12984299 | 0.76 | ESR1 (0.39) | ESR1ESR2KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL13316439 | 0.76 | ESR1 (0.39) | ESR1ESR2SMN1; SMN2PLAU | |
| SCHEMBL23540686 | 0.76 | ESR1 (0.39) | ESR1ESR2KMT2ASMN1; SMN2 | |
| SCHEMBL30015180 | 0.74 | ESR1 (0.38) | ESR1ESR2KMT2ASMN1; SMN2 | |
| SCHEMBL23540714 | 0.74 | ESR1 (0.38) | ESR1ESR2KMT2ASMN1; SMN2 | |
| SCHEMBL8444206 | 0.74 | TRPA1 (0.39) | HCAR2KMT2AKDM4EPLAUGRIN2D | |
| SCHEMBL14797873 | 0.74 | ESR1 (0.35) | ESR1ESR2KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120442-A | Tricyclic compounds useful for treating cancer, autoimmune disorders, and inflammatory disorders | 薛定谔公司 | 2023-11-24 | — | — | CN | disclosed |