Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540858 | 1.00 | HDAC2 (0.43) | HDAC2HDAC8HDAC6ALDH1A1KMT2A | |
| SCHEMBL29112295 | 1.00 | HDAC2 (0.43) | HDAC2HDAC8HDAC6ALDH1A1KMT2A | |
| SCHEMBL30626426 | 1.00 | HDAC2 (0.43) | HDAC2HDAC8HDAC6ALDH1A1KMT2A | |
| SCHEMBL29112419 | 0.87 | SMN1; SMN2 (0.43) | HDAC2HDAC8HDAC6ALDH1A1KMT2A | |
| SCHEMBL24540446 | 0.87 | SMN1; SMN2 (0.43) | HDAC2HDAC8HDAC6ALDH1A1KMT2A | |
| SCHEMBL29112421 | 0.87 | SMN1; SMN2 (0.43) | HDAC2HDAC8HDAC6ALDH1A1KMT2A | |
| SCHEMBL24540251 | 0.87 | GAA (0.44) | ALDH1A1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL29112470 | 0.87 | GAA (0.44) | ALDH1A1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL29112469 | 0.87 | GAA (0.44) | ALDH1A1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL24540726 | 0.83 | KDM4E (0.45) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |