Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29112469 | 1.00 | GAA (0.44) | GAACYP2C19MEN1KMT2ACTSB | |
| SCHEMBL29112470 | 1.00 | GAA (0.44) | GAACYP2C19MEN1KMT2ACTSB | |
| SCHEMBL29112442 | 0.91 | ALDH1A1 (0.46) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL24540726 | 0.91 | KDM4E (0.45) | GAACYP2C19MEN1KMT2ACTSB | |
| SCHEMBL29112286 | 0.91 | KDM4E (0.45) | GAACYP2C19MEN1KMT2ACTSB | |
| SCHEMBL24540469 | 0.91 | MEN1 (0.39) | GAACYP2C19MEN1KMT2ACTSB | |
| SCHEMBL24540521 | 0.91 | ALDH1A1 (0.46) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29112500 | 0.91 | MEN1 (0.39) | GAACYP2C19MEN1KMT2ACTSB | |
| SCHEMBL29112288 | 0.91 | KDM4E (0.45) | GAACYP2C19MEN1KMT2ACTSB | |
| SCHEMBL29112499 | 0.91 | MEN1 (0.39) | GAACYP2C19MEN1KMT2ACTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263493-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | Sanofi (FR) | 2023-10-25 | — | — | EP | disclosed |
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |
| WO-2022133027-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022133027-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-06-23 | — | — | WO | disclosed |