Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29112340 | 1.00 | TRPA1 (0.33) | TRPA1TRPM8EPHX1TRPV1 | |
| SCHEMBL30626437 | 1.00 | TRPA1 (0.33) | TRPA1TRPM8EPHX1TRPV1 | |
| SCHEMBL24540324 | 0.81 | GPBAR1 (0.30) | — | |
| SCHEMBL25427457 | 0.77 | TRPA1 (0.31) | TRPA1TRPM8EPHX1 | |
| SCHEMBL31152474 | 0.77 | TRPA1 (0.31) | TRPA1TRPM8EPHX1 | |
| SCHEMBL25426053 | 0.77 | TRPA1 (0.31) | TRPA1TRPM8EPHX1 | |
| SCHEMBL14515122 | 0.74 | TRPA1 (0.34) | TRPA1TRPM8 | |
| SCHEMBL1870837 | 0.74 | TRPA1 (0.34) | TRPA1TRPM8 | |
| SCHEMBL30297195 | 0.73 | — | — | |
| SCHEMBL12671701 | 0.72 | TRPA1 (0.33) | TRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |