Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20831516 | 0.76 | ITGB2 (0.72) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL27758873 | 0.74 | ITGB2 (0.48) | ITGB2ICAM1ITGALMEN1KMT2A | |
| Chromanone SCHEMBL28794 | 0.74 | MAOB (0.56) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL27548371 | 0.74 | ITGB2 (0.48) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL29388064 | 0.74 | ITGB2 (0.48) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL5173946 | 0.74 | ITGB2 (0.48) | ITGB2ICAM1ITGALMEN1KMT2A | |
| Chromanone SCHEMBL29384996 | 0.74 | MAOB (0.56) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL154144 | 0.74 | ITGB2 (0.48) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL8787503 | 0.74 | ITGB2 (0.48) | ITGB2ICAM1ITGALMEN1KMT2A | |
| Chromanone SCHEMBL28205525 | 0.74 | MAOB (0.56) | ITGB2ICAM1ITGALMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |