Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.80 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.59 |
| ▸ | BLM | P54132 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NQO2 | P16083 | 2/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23069143 | 0.90 | MTNR1A (0.64) | MTNR1AMTNR1BCYP1A2BLMMEN1 | |
| SCHEMBL29967548 | 0.90 | MTNR1A (0.64) | MTNR1AMTNR1BCYP1A2BLMMEN1 | |
| SCHEMBL27084955 | 0.89 | MTNR1A (0.74) | MTNR1AMTNR1BCYP1A2BLMMEN1 | |
| SCHEMBL27085140 | 0.89 | MTNR1A (0.74) | MTNR1AMTNR1BCYP1A2BLMMEN1 | |
| SCHEMBL25236273 | 0.89 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2BLMMEN1 | |
| SCHEMBL27084687 | 0.88 | MTNR1A (0.73) | MTNR1AMTNR1BCYP1A2BLMMEN1 | |
| SCHEMBL27085201 | 0.88 | MTNR1A (0.73) | MTNR1AMTNR1BCYP1A2BLMMEN1 | |
| SCHEMBL27085263 | 0.87 | MTNR1A (0.71) | MTNR1AMTNR1BCYP1A2BLMMEN1 | |
| SCHEMBL25029951 | 0.86 | MTNR1A (0.60) | MTNR1AMTNR1BCYP1A2BLMMEN1 | |
| SCHEMBL29112595 | 0.85 | MTNR1A (0.69) | MTNR1AMTNR1BCYP1A2BLMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120415-A | Modified indole alkaloids for therapeutic use | 指南针探路者有限公司 | 2023-11-24 | — | — | CN | disclosed |