Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 3/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27084978 | 0.96 | HTR2A (0.55) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL29112606 | 0.94 | HTR2A (0.62) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL27084681 | 0.94 | HTR2A (0.59) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL27084973 | 0.92 | HTR1A (0.58) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL27084863 | 0.92 | HTR2A (0.59) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL27085036 | 0.91 | HTR2A (0.54) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL27084685 | 0.90 | HTR2A (0.59) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL27085219 | 0.90 | HTR2A (0.60) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL27084756 | 0.90 | HTR2A (0.58) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL27084985 | 0.88 | HTR2A (0.57) | HTR2AHTR1AHTR2CHTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120415-A | Modified indole alkaloids for therapeutic use | 指南针探路者有限公司 | 2023-11-24 | — | — | CN | disclosed |