SCHEMBL29112659

SCHEMBL29112659

COC(=O)c1nc([Sn](C)(C)C)nn1C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPC1 O15118 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23214318 0.74 NPSR1 (0.40) NPSR1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL31696636 0.70 PKM (0.40) NPSR1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL26061187 0.70 NPSR1 (0.36) NPSR1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL29441637 0.63 NPSR1 (0.36) NPSR1L3MBTL1KDM4EALDH1A1
SCHEMBL5105802 0.63 NPSR1 (0.40) NPSR1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL15465491 0.62 NPSR1 (0.38) NPSR1KDM4EALDH1A1LMNAHPGD
SCHEMBL2148028 0.60 NPSR1 (0.37) NPSR1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL14186810 0.60 NPSR1 (0.41) NPSR1L3MBTL1KDM4EALDH1A1HPGD
SCHEMBL8000263 0.60 TP53 (0.38) NPSR1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL23497713 0.60 KDM4E (0.44) NPSR1L3MBTL1KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117120430-A MK2 inhibitors and uses thereof 新特拉有限公司 2023-11-24 CN disclosed