Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22490641 | 0.79 | EGLN2 (0.35) | EGLN2CHEK1MAP4K4CSF1RPRKACA | |
| SCHEMBL30881599 | 0.76 | EGLN2 (0.33) | EGLN2CHEK1MAP4K4CSF1RPRKACA | |
| SCHEMBL2571208 | 0.71 | PDE10A (0.32) | CHEK1MAP4K4CSF1RPRKACAKDR | |
| SCHEMBL24438415 | 0.68 | CHEK1 (0.31) | EGLN2CHEK1MAP4K4CSF1RPRKACA | |
| SCHEMBL14638812 | 0.67 | CHEK1 (0.32) | CHEK1MAP4K4CSF1RPRKACAKDR | |
| SCHEMBL21352246 | 0.67 | CDK8 (0.53) | CHEK1MAP4K4CSF1RPRKACAKDR | |
| SCHEMBL22490649 | 0.65 | EGLN2 (0.34) | EGLN2CHEK1MAP4K4CSF1RPRKACA | |
| SCHEMBL2571757 | 0.65 | PDE10A (0.33) | EGLN2CHEK1MAP4K4CSF1RPRKACA | |
| SCHEMBL21438499 | 0.64 | RECQL (0.39) | EGLN2RECQL | |
| SCHEMBL24448759 | 0.64 | CDK8 (0.34) | CHEK1MAP4K4CSF1RPRKACAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120439-A | FGFR3 inhibitor compounds | 伊莱利利公司 | 2023-11-24 | — | — | CN | disclosed |