Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.42 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.41 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.41 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718223 | 1.00 | PARP10 (0.52) | PARP10PARP11PDGFRBPDGFRACYP2A6 | |
| SCHEMBL15367344 | 0.78 | PDGFRB (0.51) | PARP10PARP11PDGFRBPDGFRACYP2A6 | |
| SCHEMBL29932029 | 0.77 | PIK3CA (0.49) | PARP10PARP11PDGFRBPDGFRACYP2A6 | |
| SCHEMBL27029524 | 0.77 | PIK3CA (0.49) | PARP10PARP11PDGFRBPDGFRACYP2A6 | |
| SCHEMBL24732485 | 0.76 | PDGFRB (0.55) | PARP10PARP11PDGFRBPDGFRACYP2A6 | |
| SCHEMBL12765339 | 0.76 | CHEK1 (0.45) | PARP10PARP11CYP2A6CYP1A2PIK3CA | |
| SCHEMBL31428879 | 0.75 | PDGFRB (0.57) | PDGFRBPDGFRACYP2A6CYP1A2NISCH | |
| SCHEMBL20873052 | 0.75 | PDGFRB (0.57) | PDGFRBPDGFRACYP2A6CYP1A2NISCH | |
| SCHEMBL30345250 | 0.75 | PDGFRB (0.57) | PDGFRBPDGFRACYP2A6CYP1A2NISCH | |
| SCHEMBL29375329 | 0.74 | CYP1A2 (0.56) | PARP10PARP11PDGFRBPDGFRACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157284-A | CTLA-4 small molecule degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |