Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096081 | 0.81 | HSD11B1 (0.37) | MAPTAPPASIC3HTTLMNA | |
| SCHEMBL29096086 | 0.81 | ACACB (0.38) | MAPTASIC3HTTLMNAKMT2A | |
| SCHEMBL29096084 | 0.81 | MAPT (0.43) | MAPTNPSR1ASIC3LMNASMN1; SMN2 | |
| SCHEMBL29116861 | 0.81 | RARB (0.46) | MAPTASIC3HTTLMNASMN1; SMN2 | |
| SCHEMBL487465 | 0.81 | MAPT (0.56) | MAPTAPPNPSR1ASIC3NPC1 | |
| SCHEMBL29116860 | 0.81 | GRM5 (0.42) | MAPTASIC3 | |
| SCHEMBL29096090 | 0.80 | KCNH2 (0.44) | MAPTKCNH2KMT2A | |
| SCHEMBL30597666 | 0.80 | KCNH2 (0.44) | MAPTKCNH2KMT2A | |
| SCHEMBL10723498 | 0.78 | MAPT (0.50) | MAPTAPPNPSR1NPC1RAB9A | |
| SCHEMBL18561130 | 0.78 | MAPT (0.53) | MAPTAPPASIC3HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969820-A | Method for realizing visible light-induced intramolecular alkynyl migration of 1, 4-eneyne compound and realizing unactivated olefin difunctional | 哈尔滨工业大学 | 2023-10-31 | — | — | CN | disclosed |