SCHEMBL2911799 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	1/20	0.40

▸	SMN1; SMN2	Q16637	1/20	0.40

▸	GSK3B	P49841	4/20	0.39

▸	GSK3A	P49840	3/20	0.39

▸	DCAF1	Q9Y4B6	1/20	0.37

▸	MAPK1	P28482	13/20	0.37

▸	CDK1	P06493	2/20	0.36

▸	CCNB2	O95067	1/20	0.35

▸	CCNB1	P14635	1/20	0.35

▸	CCNB3	Q8WWL7	1/20	0.35

▸	FOLH1	Q04609	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2910313	1.00	ALDH1A1 (0.40)	ALDH1A1SMN1; SMN2GSK3BGSK3ADCAF1
SCHEMBL2911532	0.92	ALDH1A1 (0.41)	ALDH1A1SMN1; SMN2GSK3BGSK3AMAPK1
SCHEMBL2910371	0.92	ALDH1A1 (0.41)	ALDH1A1SMN1; SMN2GSK3BGSK3AMAPK1
SCHEMBL2910831	0.89	GSK3B (0.48)	ALDH1A1SMN1; SMN2GSK3BGSK3ACDK1
SCHEMBL12892551	0.89	GSK3B (0.48)	ALDH1A1SMN1; SMN2GSK3BGSK3ACDK1
SCHEMBL2904789	0.89	GSK3B (0.48)	ALDH1A1SMN1; SMN2GSK3BGSK3ACDK1
SCHEMBL2910067	0.88	GSK3B (0.47)	ALDH1A1SMN1; SMN2GSK3BGSK3AMAPK1
SCHEMBL2912143	0.88	SMN1; SMN2 (0.40)	ALDH1A1SMN1; SMN2GSK3BGSK3ADCAF1
SCHEMBL2908086	0.88	GSK3B (0.47)	ALDH1A1SMN1; SMN2GSK3BGSK3AMAPK1
SCHEMBL2910075	0.88	SMN1; SMN2 (0.40)	ALDH1A1SMN1; SMN2GSK3BGSK3ADCAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1537099-B1	PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3	NOVARTIS VACCINES & DIAGNOSTIC (US)	2010-08-11	—	—	EP	disclosed