Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 3/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | POLG | P54098 | 1/20 | 0.45 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265361 | 0.95 | FAP (0.49) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2912509 | 0.87 | FAP (0.32) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2906241 | 0.81 | FAP (0.34) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2911836 | 0.80 | FAP (0.69) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2912875 | 0.80 | FAP (0.54) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL4968516 | 0.77 | POLB (0.32) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2905475 | 0.76 | FAP (0.62) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2904496 | 0.74 | FGFR1 (0.61) | SLC22A6AHCYFGFR1METTL3METTL14 | |
| SCHEMBL13328610 | 0.74 | CYP3A4 (0.50) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2912968 | 0.74 | FAP (0.62) | FAPSLC22A6ABCB11POLA1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |