Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481939 | 0.81 | ROCK2 (0.34) | ROCK2BCHEHTTATMFAAH | |
| SCHEMBL18603273 | 0.79 | KCNH2 (0.34) | ROCK2BCHEHTTATMFAAH | |
| SCHEMBL4699798 | 0.79 | ROCK2 (0.36) | ROCK2BCHEHTTATMFAAH | |
| SCHEMBL30771246 | 0.79 | AR (0.34) | ROCK2BCHEHTTATMFAAH | |
| SCHEMBL23751758 | 0.76 | HTT (0.37) | ROCK2HTTATMGPR119 | |
| SCHEMBL581742 | 0.76 | KCNH2 (0.35) | ROCK2HTTATMGPR119 | |
| SCHEMBL18387648 | 0.75 | EPHX2 (0.47) | ROCK2HTTELANEGPR119 | |
| SCHEMBL28574885 | 0.75 | ROCK2 (0.34) | ROCK2BCHE | |
| Boric Acid SCHEMBL29391967 | 0.72 | ELANE (0.44) | ROCK2BCHEHTTATMELANE | |
| SCHEMBL17631624 | 0.71 | HDAC8 (0.39) | ROCK2BCHEHTTKDM1ASCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112930348-B | Improved process for the manufacture of 3- [ (1S) -1-imidazo [1,2-a ] pyridin-6-ylethyl ] -5- (1-methylpyrazol-4-yl) triazolo [4,5-b ] pyrazines and polymorphic forms thereof | 阿斯利康(瑞典)有限公司 | 2023-12-05 | — | — | CN | disclosed |