Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29996709 | 0.87 | PRMT1 (0.47) | PRMT1NAMPTMAP4K4CYP17A1MEN1 | |
| SCHEMBL1478008 | 0.87 | PRMT1 (0.47) | PRMT1NAMPTMAP4K4CYP17A1MEN1 | |
| SCHEMBL15528796 | 0.86 | MEN1 (0.41) | PRMT1NAMPTMAP4K4MEN1POLB | |
| SCHEMBL29996399 | 0.86 | MEN1 (0.49) | PRMT1NAMPTMAP4K4CYP17A1MEN1 | |
| SCHEMBL28863219 | 0.86 | MEN1 (0.49) | PRMT1NAMPTMAP4K4CYP17A1MEN1 | |
| SCHEMBL29996697 | 0.83 | CDK8 (0.46) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL4732688 | 0.83 | CDK8 (0.46) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL18650610 | 0.82 | BCHE (0.43) | PRMT1MEN1KMT2ACA12CA1 | |
| SCHEMBL13636098 | 0.81 | PRMT1 (0.40) | PRMT1MAP4K4MEN1POLBKMT2A | |
| SCHEMBL31363779 | 0.80 | NAMPT (0.51) | PRMT1NAMPTMAP4K4CYP17A1PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240368168-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND APPLICATION THEREOF | ARTIVILA BIOPHARMA (CN) | 2024-11-07 | — | — | US | disclosed |
| CN-117751117-A | SARM1 enzyme activity inhibitor and application thereof | 科辉智药生物科技（无锡）有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-115724839-A | SARM1 enzyme activity inhibitor and application thereof | 科辉智药生物科技(深圳)有限公司 | 2023-03-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368168-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND APPLICATION THEREOF | SARM1, BACE1, SARNP | PRMT1 174/4885NAMPT 1313/4885MAP4K4 2006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.