Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL247056 | 0.91 | USP2 (0.47) | USP2LMNAKDM4EDUSP3MEN1 | |
| Propene SCHEMBL10437872 | 0.89 | USP2 (0.45) | USP2LMNAKDM4EDUSP3MEN1 | |
| Propene SCHEMBL8029718 | 0.89 | USP2 (0.45) | USP2LMNAKDM4EDUSP3MEN1 | |
| Sulfuric Acid SCHEMBL9903961 | 0.86 | USP2 (0.40) | USP2LMNAKDM4EDUSP3MEN1 | |
| Acrylic Acid SCHEMBL29407010 | 0.85 | LMNA (0.43) | USP2LMNAKDM4EDUSP3MEN1 | |
| Acrylic Acid SCHEMBL28607050 | 0.85 | LMNA (0.43) | USP2LMNAKDM4EDUSP3MEN1 | |
| Glycerin SCHEMBL28946950 | 0.84 | LMNA (0.47) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Acetaldehyde SCHEMBL7501450 | 0.84 | USP2 (0.48) | USP2LMNAKDM4EDUSP3MEN1 | |
| Acetic Acid SCHEMBL27310521 | 0.82 | USP2 (0.47) | USP2LMNAKDM4EDUSP3MEN1 | |
| Bicarbonate SCHEMBL10632366 | 0.82 | CA1 (0.57) | USP2LMNAKDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117175002-A | Solid electrolyte membrane based on solvent structure, lithium battery and preparation method thereof | 江苏厚生新能源科技股份有限公司 | 2023-12-05 | — | — | CN | disclosed |