Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15650054 | 0.81 | PARP10 (0.44) | PARP10ALDH1A1 | |
| SCHEMBL15083519 | 0.80 | CA1 (0.42) | HDAC8HDAC3MEN1KMT2ACA2 | |
| SCHEMBL30437401 | 0.80 | KMT2A (0.50) | MEN1KMT2ACA2PARP10LMNA | |
| SCHEMBL15095783 | 0.79 | HDAC1 (0.33) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL14270206 | 0.77 | HDAC3 (0.51) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL28527802 | 0.76 | HDAC1 (0.54) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL14189703 | 0.75 | HDAC3 (0.45) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL29710019 | 0.75 | TRPA1 (0.38) | MEN1KMT2APARP10PLAULMNA | |
| SCHEMBL2297635 | 0.74 | PARP10 (0.54) | CA2PARP10ALDH1A1CA9 | |
| SCHEMBL27519597 | 0.74 | POLB (0.57) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177958-A | Small molecule modulators of alveolar type 2cell proliferation for the treatment of pulmonary diseases | 斯克里普斯研究学院 | 2023-12-05 | — | — | CN | disclosed |