SCHEMBL29121192

SCHEMBL29121192

CC(C)Oc1ccc(-c2cc3c(cc2F)[C@H](OC(N)=O)C(C)(C)C3)cc1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28828458 1.00 FFAR4 (0.42) FFAR4
SCHEMBL29121218 0.90 KDM1A (0.39) FFAR4
SCHEMBL28828494 0.90 KDM1A (0.39) FFAR4
SCHEMBL27200883 0.90 FFAR4 (0.41) FFAR4
SCHEMBL29121175 0.90 FFAR4 (0.41) FFAR4
SCHEMBL28828510 0.89 PRKAB2 (0.39)
SCHEMBL29121219 0.89 PRKAB2 (0.39)
SCHEMBL29121211 0.88 ACACB (0.35) FFAR4
SCHEMBL29121313 0.88 FFAR4 (0.42) FFAR4
SCHEMBL28828612 0.88 APP (0.37) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117222645-A Novel compound having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salt thereof, process for producing the same, and pharmaceutical composition containing the same 柳韩洋行 2023-12-12 CN claimed
CN-117222645-A Novel compound having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salt thereof, process for producing the same, and pharmaceutical composition containing the same 柳韩洋行 2023-12-12 CN disclosed