Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 4/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.39 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30676388 | 1.00 | BTK (0.45) | BTKUSP30IDO1TDO2KRAS | |
| SCHEMBL29121705 | 1.00 | BTK (0.45) | BTKUSP30IDO1TDO2KRAS | |
| SCHEMBL29121569 | 1.00 | BTK (0.45) | BTKUSP30IDO1TDO2KRAS | |
| SCHEMBL30676570 | 1.00 | BTK (0.45) | BTKUSP30IDO1TDO2KRAS | |
| SCHEMBL29121677 | 0.86 | USP30 (0.46) | BTKUSP30IDO1TDO2KRAS | |
| SCHEMBL30676433 | 0.86 | USP30 (0.46) | BTKUSP30IDO1TDO2KRAS | |
| SCHEMBL30676577 | 0.86 | USP30 (0.46) | BTKUSP30IDO1TDO2KRAS | |
| SCHEMBL29122756 | 0.85 | USP30 (0.45) | BTKUSP30IDO1TDO2KRAS | |
| SCHEMBL29122133 | 0.85 | USP30 (0.45) | BTKUSP30IDO1TDO2KRAS | |
| SCHEMBL29122350 | 0.85 | TEAD1 (0.37) | BTKKRASFPR2EGFRCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |